Is the ‘default mode network’ responsible for the mental health crisis in youth?
(Note: I now also wrote up this blog post as a commentary that I submitted to the editor of the journal.) The very short answer is: no, youth mental health… Read more »
Category Archives: Biomarkers
“Clear evidence” for serotonin hypothesis of depression?
There has been a 60 year long discussion on the role of the neurotransmitter serotonin in the pathophysiology of depression. A recent systematic investigation by Joanna Moncrieff and colleagues concluded… Read more »
All mental disorders are brain disorders … not.
TL;DR: Mental disorders are commonly defined as “brain disorders” in the literature, and the current funding structure in psychiatry and clinical psychology is strongly based on this notion. At least… Read more »
Molecular Psychiatry commentary: Fried & Kievit 2015
On December 15th, Molecular Psychiatry published our commentary “The volumes of subcortical regions in depressed and healthy individuals are strikingly similar: a reinterpretation of the results by Schmaal et al”…. Read more »
Overinterpretation of SSRI study results: Halaris et al. 2015
Halaris and colleagues published a paper in the Journal of Psychiatric Research in which they studied the impact of the SSRI antidepressant escitalopram (ESC) in a group of 30 depressed… Read more »
How to not interpret novel drug results: Fava et al. 2015
Imagine you are the editor of, or reviewer for, a very prestigious scientific journal, and you receive a paper about the efficacy of a novel drug for, say, cancer or… Read more »
The genetics of major depression remain elusive
Nature didn’t want our commentary ;) … so we publish it here instead. A commentary by Eiko Fried, Sophie van der Sluis, and Angelique Cramer (PDF) A recent study published in… Read more »
Nature correspondence published
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Our commentary regarding the NIMH’s decision to solely fund research investigating the neurobiological roots of mental disorders was published in today’s issue of Nature. » Fried, E. I., Tuerlinckx, F.,… Read more »