There has been a 60 year long discussion on the role of the neurotransmitter serotonin in the pathophysiology of depression. A recent systematic investigation by Joanna Moncrief and colleagues concluded… Read more »
It’s been a while since I wrote a blog post on a new paper, but the recently published paper of Jill de Ron et al. investigates limitations of network models… Read more »
There was a lot of hype in the last days around a new study on treating major depressive disorder via psilocybin, the active ingredient of magic mushrooms. In the paper… Read more »
Young Academy Leiden challenged its members—including yours truly—to make a video about an upcoming research project, with two constraints. First, we only have one minute to communicate our idea. Second,… Read more »
Led by the first author Kaat Hebbrecht, we published an open access paper a few days ago on “Understanding personalized dynamics to inform precision medicine: a dynamic time warp analysis… Read more »
I’m extremely happy, proud, humbled, and somewhat nervous announce that my application for an European Research Council (ERC) Starting Grant was successful (on my first try!), following the announcement by… Read more »
Our team led by the brilliant Astrid Chevance just published a new paper, entitled “Identifying outcomes for depression that matter to patients, informal caregivers and healthcare professionals: qualitative content analysis… Read more »
A new study on candidate genes for depression was just published in the American Journal of Psychiatry by Border et al, entitled “No Support for Historical Candidate Gene or Candidate… Read more »
This blog post is the result of a collaboration between Dr Lucy Robinson (Twitter, email) & me. Life with depression can be miserable, painful and sad. The suffering it causes… Read more »
We wrote up the core arguments and calculations of this blog post as an article for Lancet Psychiatry. Major depression: a highly heterogeneous disorder Major Depressive Disorder (MDD) is a… Read more »
I had the honor to chair 2 symposia at the International Convention of Psychological Science in Vienna the last days, and gave 3 talks. You can find all presentations below.
I wrote this commentary together with Adam Chekroud. You can find a PDF version of this commentary here. Introduction The largest and longest investigation of treatment-resistant depression (TRD) to date,… Read more »
I published a new paper in the Journal of Affective Disorders entitled “The 52 symptoms of major depression: Lack of content overlap among seven common depression scales” (PDF). The paper… Read more »
After reviewing the paper “The relative responsiveness of test instruments can be estimated using a meta-analytic approach: an illustration with treatments for depression” by Kounali et al. 2016, the editor… Read more »
Imagine you are a group of scientists and want to find out whether a novel drug X works on a specific problem Y. You run the following study: You enroll… Read more »