This is one of these blog posts that doesn’t read well if you stop halfway. First, I provide evidence that academia can look pretty broken: there is low-quality work everywhere you look, the peer-review system has long outlived its utility, and academic publishing is a dumpster fire. Add considerable work pressure, the publish-or-perish culture, and… Read more »
A new paper was published yesterday on a blood test for schizophrenia, by the same research team that in 2021 published a paper on a blood test for depression. The papers and accompanying press release contain problematic language, and the general idea of a blood test for mental illness makes very little sense to me… Read more »
A new interesting paper was published 2 weeks ago on depression and temperature. I saw a news article about the paper today that I didn’t think captured the core findings particularly well — and I wasn’t happy with some of the authors’ conclusions either — so I briefly wanted to summarize these issues here. Study… Read more »
(Note: I wrote up this blog as a commentary, which is now published in the same journal as response to the editorial. PDF, DOI 10.31234/osf.io/eycvw) The very short answer is: no, youth mental health problems are not generally due to the default mode network (DMN). But the editorial in Current Psychiatry that claims it may… Read more »
Mental health problems are comorbid, which means that they are positively intercorrelated and don’t tend to occur in isolation. Of all people diagnosed with major depression, for example, about half of them have at least one more comorbid mental health problem, such as generalized anxiety disorder or posttraumatic stress disorder. Now, the same holds for… Read more »
I have been playing around with GPT-3 and its chatbot in previous weeks, and found it fascinating. GPT-3——the Generative Pre-trained Transformer 3——is a deep learning language model developed by OPEN AI and produces human-like text. Some amazing use cases have already been explored. Here is an example where Denny Borsboom interrogated GPT-3 about assumptions of… Read more »
There has been a 60 year long discussion on the role of the neurotransmitter serotonin in the pathophysiology of depression. A recent systematic investigation by Joanna Moncrieff and colleagues concluded that “main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis… Read more »
It’s been a while since I wrote a blog post on a new paper, but the recently published paper of Jill de Ron et al. investigates limitations of network models discussed for a good decade now, and I’m very happy it’s online (URL, PDF). As many of you know, network models in our field often… Read more »
In December 2021, Robin Kok wrote a series of tweets about his Elsevier data access request. I did the same a few days later. This here is the resulting collaborative blog post, summarizing our journey in trying to understand what data Elsevier collects; what data Elsevier has collected on us two specifically; and trying to… Read more »
About a year ago, the Association for Psychological Science awarded me with the Janet Taylor Spence Award for transformative early career contributions to psychological science. Given that I often move on too quickly into the next big thing rather than taking stock a little when good things happen, I wanted to write a short blog… Read more »
Update, 02/2024: We have now published the paper “History repeating: guidelines to address common problems in psychedelic science” on this topic, in part based on this blog post. We introduces 10 pressing challenges that limit conclusions regarding safety and efficacy. We share a checklist that researchers, journalists, funders, policymakers, and other stakeholders can use to… Read more »
We just finished collecting the first cohort of the WARN-D study, our ambitious effort to create a personalized early warning system for depression. In the 90 minute self report survey, we try to get at many of the most relevant predicators for depression onset. Creating this battery took us many months, and involved a delphi… Read more »
Update: the paper is now published in Current Directions in Psychological Science; you can find my summary of the paper on Twitter. I’ve written a very brief piece on embracing the complexity of mental health problems, entitled “Studying mental disorders as systems, not syndromes” (download). I also had the opportunity to give a keynote on… Read more »
For our new WARN-D research project on building a personalized early warning system for depression, I recently looked into openly available, transdiagnostic, self-report mental health screeners. The most common recommendation was to use the DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure (Adult). This measure was released by the American Psychiatric Association (APA) — the organization… Read more »
Young Academy Leiden challenged its members—including yours truly—to make a video about an upcoming research project, with two constraints. First, we only have one minute to communicate our idea. Second, as toolkit, we can only use LEGOs from the ‘creative suitcase’ we all received, a small box of LEGOs. Here’s my short video, about my… Read more »